SkinMedica® HA⁵® Hydra Collagen Replenish + Restore Hydrator

SkinMedica® HA⁵® Hydra Collagen Replenish + Restore Hydrator

Advanced Hydration for All Skin Types
Size: 2 oz. | TSA-Friendly

Meet the next evolution in SkinMedica’s award-winning HA⁵® hydration line. This upgraded formula delivers 2X more hyaluronic acid, now enhanced with Hydra Collagen and Advanced VITISENSCE® Technology to provide instant, long-lasting moisture, visibly plumper skin, and fewer fine lines. Ideal for all skin types—including dry, dehydrated, and sensitive skin.

Why You’ll Love It

• Instantly hydrates and plumps for dewy, youthful-looking skin
• Provides up to 48 hours of hydration
• Clinically shown to visibly improve fine lines, skin barrier, and radiance
• Vegan collagen, fragrance-free, non-comedogenic, and silicone-free
• Lightweight, non-pilling, and designed to layer easily under other products

Key Benefits

• Attracts and retains water for deep, lasting hydration
• Improves the appearance of skin plumpness, texture, and tone
• Helps restore the skin’s hydration reservoir and natural humectants
• Patients reported looking ~3 years younger by Week 12 in clinical studies

Behind the Formula: Why It Works

This next-gen hydrator combines the power of Hydra Collagen Complex and Advanced VITISENSCE® Technology to support the skin’s hydration cycle—attracting, replenishing, and locking in moisture at every level of the skin. With 5 forms of HA and naturally derived oils and antioxidants, this formula addresses both dehydration and barrier support for immediate and long-term skin transformation.

Key Ingredients

HA⁵® Hydra Collagen Complex

• Hydra Collagen – A vegan collagen that draws in water and smooths skin
• 5 Types of HA:
  • Vectorized Time-Release HA – slow-release hydration
  • Cross-Linked HA – long-lasting moisture retention
  • Liposomal HA – deep penetration and fast hydration
  • Noncross-linked HA – smoothing surface hydration
  • Nano HA – calming hydration and barrier support

Advanced VITISENSCE® Technology

• Vitis Flower Stem Cell + Lotus Sprout Extracts – Protect against oxidative stress
• Avocado Oil Esters + Passion Fruit Seed Oil – Help strengthen the skin barrier and improve hydration
• Vitamin F (Linoleic Acid) – Reinforces barrier function and reduces water loss

How to Use

When to Apply
Morning and evening—after cleansing and serums but before moisturizer or SPF.

Where to Apply
Face, neck, and chest (or any area in need of hydration and smoothing).

How to Apply
Dispense 1–2 pumps and smooth evenly onto damp skin. Avoid eye area. If contact occurs, rinse thoroughly with water.

Clinical Results

• 93% reported skin looked dewy and healthy at 2 weeks
• 93% reported visibly plumper skin at 12 weeks
• 97% agreed skin quality improved at 12 weeks
• 100% felt more confident in their skin after 12 weeks

Additional Information

How is this different from the original HA⁵® Rejuvenating Hydrator?
This modernized formula contains 2X the hyaluronic acid, adds vegan Hydra Collagen, and offers 48-hour hydration (compared to 24). It also features upgraded VITISENSCE® Technology for deeper and longer-lasting results.

Hydrator vs. Moisturizer:
A moisturizer prevents water loss, while a hydrator actively attracts and retains water to improve the skin’s own hydration mechanisms.

Dry vs. Dehydrated Skin:
Dry skin is a type (low in oil); dehydrated skin is a condition (low in water). This formula addresses both by supporting the skin barrier and replenishing lost moisture.

Where it fits in your regimen:
Use before your moisturizer to amplify hydration and help lock in all treatment products.

Full Ingredient List

Aqua/Water/Eau, Glycerin, Caprylic/Capric Triglyceride, Shorea Stenoptera Seed Butter, C9-12 Alkane, Propanediol, Linoleic Acid, Sodium Acrylates Copolymer, Passiflora Edulis Seed Oil, Sodium Hyaluronate, Hydrolyzed Hyaluronic Acid, Sodium Hyaluronate Crosspolymer, Nelumbo Nucifera Germ Extract, Collagen, Butyl Avocadate, Trehalose, Serine, Vitis Vinifera (Grape) Flower Cell Extract, Linolenic Acid, Urea, Caprylhydroxamic Acid, Algin, Polyglutamic Acid, Tocopherol, Oleic Acid, Pullulan, Palmitic Acid, Glyceryl Glucoside, Coco-Caprylate/Caprate, Lecithin, 1,2-Hexanediol, Pentylene Glycol, Stearic Acid, Benzoic Acid, Caprylyl Glycol, Polysorbate 20, Dehydroacetic Acid, Glyceryl Polyacrylate, Potassium Phosphate, Benzyl Alcohol, Disodium Phosphate, Sodium Benzoate